MolNFT v1 · #133893 · protein
Structures of product and inhibitor complexes of streptomyces griseus protease a at 1.8 ångströms resolution. a model for serine protease catalysis
5SGA · Proteinase a (sgpa): “Structures of product and inhibitor complexes of streptomyces griseus protease a at 1.8 ångströms resolution.…”. X-ray diffraction, 1 ligand (ACE). MolNFT v1 #133893 on GenesisL1: 3D structure, binding sites…
- PDB
- 5SGA
- Type
- protein
- Length
- 185 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Proteinase a (sgpa); Tetrapeptide ACE-pro-ala-pro-tyr
- UniProt
- P00776
- Ligands
- ACE
Structure
x-ray diffraction · 2 distinct chains · 10% helix, 55% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | Proteinase a (sgpa) | protein | 181 | 10% helix, 55% strand | P00776 |
| P | Tetrapeptide ACE-pro-ala-pro-tyr | protein | 4 | 0% helix, 50% strand | — |
Ligands and binding sites
- ACE · Acetyl group · ligand · chains E, P
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- E–P · 395 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide, 1 covalent (disulfide, covalent ligand).
Compared structures
- 5SGA · Structures of product and inhibitor complexes of Streptomyces griseus protease a at 1.8… · the same entry in another collection · chain E against E, TM-score 1.00
- P00776 · AlphaFold monomer V2.0 prediction for streptogrisin-a (P00776) · a predicted model of the same protein · chain E against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00776
- Elsewhere: RCSB PDB 5SGA · PDBe 5SGA · UniProt P00776
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