MolNFT v1 · #13319 · protein
TYR44PHE mutant of bacterial cocaine esterase coce
1L7R: “TYR44PHE mutant of bacterial cocaine esterase coce”. X-ray diffraction, 4 pockets (best druggability 0.60). MolNFT v1 #13319 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1L7R
- Type
- protein
- Length
- 573 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cocaine esterase
- EC
- 3.1.1.1
- UniProt
- Q9L9D7
- Pockets
- 4 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 23% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cocaine esterase (EC 3.1.1.1) | protein | 573 | 23% helix, 31% strand | Q9L9D7 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 198 | 0.60 | 0.81 | 29 | empty |
| 2 | 94 | 0.52 | 0.83 | 21 | empty |
| 3 | 79 | 0.36 | 0.76 | 18 | empty |
| 4 | 89 | 0.33 | 0.74 | 21 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9L9D7
- Elsewhere: RCSB PDB 1L7R · PDBe 1L7R · UniProt Q9L9D7
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