MolNFT v1 · #1328 · protein
Crystal structures of peptide complexes of the amino- terminal SH2 domain of the syp tyrosine phosphatase
1AYB · Protein-tyrosine phosphatase syp (N-terminal SH2 domain): “Crystal structures of peptide complexes of the amino- terminal SH2 domain of the syp tyrosine phosphatase”. X-ray diffraction. MolNFT v1 #1328 on GenesisL1: 3D structure…
- PDB
- 1AYB
- Type
- protein
- Length
- 108 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein-tyrosine phosphatase syp (N-terminal SH2 domain); Peptide irs-1-895
- EC
- 3.1.3.48
- UniProt
- P35235, P35569
Structure
x-ray diffraction · 2 distinct chains · 19% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein-tyrosine phosphatase syp (N-terminal SH2 domain) (EC 3.1.3.48) | protein | 100 | 20% helix, 31% strand | P35235 |
| P | Peptide irs-1-895 | protein | 8 | 0% helix, 63% strand | P35569 |
Interfaces
1 interface between chains.
- A–P · 623 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 1AYB · Crystal structures of peptide complexes of the amino-terminal SH2 domain of the syp… · the same entry in another collection · chain A against A, TM-score 1.00
- P35235 · AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase non-receptor type 11… · a predicted model of the same protein · chain A against A, TM-score 0.93
- P35569 · AlphaFold monomer V2.0 prediction for insulin receptor substrate 1 (P35569) · a predicted model of the same protein · chain P against A, TM-score 0.55
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35235
- Every structure of UniProt P35569
- Elsewhere: RCSB PDB 1AYB · PDBe 1AYB · UniProt P35235 · UniProt P35569
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