MolNFT v1 · #13213 · protein

Crystal structure of the periplasmic chaperone sfae

1L4I · Sfae protein: “Crystal structure of the periplasmic chaperone sfae”. X-ray diffraction, 3 pockets (best druggability 0.79). MolNFT v1 #13213 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1L4I
Type: protein
Length: 378 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sfae protein
UniProt: P62609
Pockets: 3 · best druggability 0.79

Structure

x-ray diffraction · 2 distinct chains · 3% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sfae protein	protein	189	3% helix, 52% strand	P62609
B	Sfae protein	protein	189	4% helix, 53% strand	P62609

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1181	0.79	0.80	89	empty
2	301	0.59	0.78	35	empty
3	66	0.48	0.84	18	empty

Interfaces

1 interface between chains.

A–B · 1051 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

1L4I · Crystal Structure of the Periplasmic Chaperone SfaE · the same entry in another collection · chain A against A, TM-score 1.00
P62609 · AlphaFold monomer V2.0 prediction for chaperone protein focc (P62609) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P62609
Elsewhere: RCSB PDB 1L4I · PDBe 1L4I · UniProt P62609

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