MolNFT v1 · #132098 · protein
Group deposition of library data - crystal structure of ecdsba after initial refinement with no ligand modelled (structure H6_1)
5QNC · THIOL:DISULFIDE interchange protein: “Group deposition of library data - crystal structure of ecdsba after initial refinement with no ligand…”. X-ray diffraction, 5 pockets (best druggability 0.60). MolNFT v1 #132098 on GenesisL1…
- PDB
- 5QNC
- Type
- protein
- Length
- 376 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- THIOL:DISULFIDE interchange protein
- UniProt
- A0A073FPA6
- Pockets
- 5 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | THIOL:DISULFIDE interchange protein | protein | 188 | 54% helix, 11% strand | A0A073FPA6 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 182 | 0.60 | 0.82 | 26 | empty |
| 2 | 266 | 0.55 | 0.76 | 41 | empty |
| 3 | 53 | 0.44 | 0.83 | 17 | empty |
| 4 | 143 | 0.41 | 0.74 | 19 | empty |
| 5 | 70 | 0.33 | 0.75 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 765 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A073FPA6
- Elsewhere: RCSB PDB 5QNC · PDBe 5QNC · UniProt A0A073FPA6
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