MolNFT v1 · #132046 · protein

Group deposition of library data - crystal structure of ecdsba after initial refinement with no ligand modelled (structure D3_1)

5QLW · THIOL:DISULFIDE interchange protein: “Group deposition of library data - crystal structure of ecdsba after initial refinement with no ligand…”. X-ray diffraction, 4 pockets (best druggability 0.59). MolNFT v1 #132046 on GenesisL1…

PDB: 5QLW
Type: protein
Length: 376 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: THIOL:DISULFIDE interchange protein
UniProt: A0A073FPA6
Pockets: 4 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 53% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	THIOL:DISULFIDE interchange protein	protein	188	53% helix, 11% strand	A0A073FPA6

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	170	0.59	0.82	24	empty
2	329	0.57	0.76	46	empty
3	126	0.40	0.75	14	empty
4	104	0.36	0.74	15	empty

Interfaces

1 interface between chains.

A–B · 799 Å² buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

5QLW · Group deposition of library data - Crystal Structure of EcDsbA after initial refinement… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A073FPA6
Elsewhere: RCSB PDB 5QLW · PDBe 5QLW · UniProt A0A073FPA6

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.