MolNFT v1 · #1318 · protein
Anti taq Fab TP7
1AY1 · TP7 Fab: “Anti taq Fab TP7”. X-ray diffraction, 5 pockets (best druggability 0.60). MolNFT v1 #1318 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1AY1
- Type
- protein
- Length
- 423 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- TP7 Fab
- UniProt
- Q91W12
- Pockets
- 5 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 4% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | TP7 Fab | protein | 210 | 6% helix, 52% strand | Q91W12 |
| H | TP7 Fab | protein | 213 | 3% helix, 51% strand | — |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 279 | 0.60 | 0.79 | 42 | empty |
| 2 | 94 | 0.40 | 0.76 | 13 | empty |
| 3 | 60 | 0.31 | 0.76 | 13 | empty |
| 4 | 55 | 0.31 | 0.76 | 15 | empty |
| 5 | 68 | 0.27 | 0.72 | 16 | empty |
Interfaces
1 interface between chains.
- L–H · 1666 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 1AY1 · Anti taq Fab TP7 · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q91W12
- Elsewhere: RCSB PDB 1AY1 · PDBe 1AY1 · UniProt Q91W12
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