MolNFT v1 · #131022 · protein
Phosphatidylinositol-specific phospholipase C mutant H32A
5PTD: “Phosphatidylinositol-specific phospholipase C mutant H32A”. X-ray diffraction, 1 pocket (best druggability 0.52). MolNFT v1 #131022 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5PTD
- Type
- protein
- Length
- 296 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphatidylinositol-specific phospholipase C
- EC
- 3.1.4.10
- UniProt
- P14262
- Pockets
- 1 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol-specific phospholipase C (EC 3.1.4.10) | protein | 296 | 30% helix, 21% strand | P14262 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 157 | 0.52 | 0.79 | 30 | empty |
Compared structures
- 5PTD · Phosphatidylinositol-specific phospholipase C mutant H32A · the same entry in another collection · chain A against A, TM-score 1.00
- P14262 · AlphaFold monomer V2.0 prediction for 1-phosphatidylinositol phosphodiesterase (P14262) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14262
- Elsewhere: RCSB PDB 5PTD · PDBe 5PTD · UniProt P14262
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