MolNFT v1 · #129846 · protein
Crystal structure of crebbp bromodomain complexed with DSPB2A002
5OWK · Creb-binding protein: “Crystal structure of crebbp bromodomain complexed with DSPB2A002”. X-ray diffraction, 1 ligand (7MX), 1 pocket (best druggability 0.43). MolNFT v1 #129846 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5OWK
- Type
- protein
- Length
- 114 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Creb-binding protein
- EC
- 2.3.1.48
- UniProt
- Q92793
- Ligands
- 7MX
- Pockets
- 1 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 63% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Creb-binding protein (EC 2.3.1.48) | protein | 114 | 63% helix, 0% strand | Q92793 |
Ligands and binding sites
- 7MX · ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 62 | 0.43 | 0.81 | 16 | 7MX |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92793
- Elsewhere: RCSB PDB 5OWK · PDBe 5OWK · UniProt Q92793
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