MolNFT v1 · #129829 · protein

Crystal structure of a C-terminally truncated trimeric ectodomain of the arabidopsis thaliana gamete fusion protein HAP2

5OW3 · Protein hapless 2: “Crystal structure of a C-terminally truncated trimeric ectodomain of the arabidopsis thaliana gamete fusion…”. X-ray diffraction, 2 ligands (NAG, ZN), 1 pocket (best druggability 0.66). MolNFT v1 #129829 on…

PDB: 5OW3
Type: protein
Length: 446 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein hapless 2
UniProt: F4JP36
Ligands: NAG, ZN
Pockets: 1 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 7% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
C	Protein hapless 2	protein	446	7% helix, 44% strand	F4JP36

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains C
ZN · Zinc ion · metal · 3 copies · chains C
GOL · Glycerol · additive · 5 copies · chains C
ACT · Acetate ion · additive · chains C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	580	0.66	0.76	61	GOL

Modifications

Observed in the structure: 7 disulfide, 2 glycan (disulfide, N-glycosylation).

Compared structures

F4JP36 · AlphaFold monomer V2.0 prediction for protein hapless 2 (F4JP36) · a predicted model of the same protein · chain C against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt F4JP36
Elsewhere: RCSB PDB 5OW3 · PDBe 5OW3 · UniProt F4JP36

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