MolNFT v1 · #129709 · protein
Crystal structure of aurora-a kinase in complex with an allosterically binding fragment
5OSE: “Crystal structure of aurora-a kinase in complex with an allosterically binding fragment”. X-ray diffraction, 3 ligands (ADP, A98, MG). MolNFT v1 #129709 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5OSE
- Type
- protein
- Length
- 265 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O14965
- Ligands
- ADP, A98, MG
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 265 | — | O14965 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- A98 · Methyl ~{N}-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl) carbamate · ligand · chains A
- MG · Magnesium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5OSE · Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment · the same entry in another collection · chain A against A, TM-score 1.00
- O14965 · AlphaFold monomer V2.0 prediction for aurora kinase a (O14965) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14965
- Elsewhere: RCSB PDB 5OSE · PDBe 5OSE · UniProt O14965
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