MolNFT v1 · #129519 · protein
Crystal structure of amycolatopsis cytochrome P450 gcoa in complex with guaethol.
5OMS: “Crystal structure of amycolatopsis cytochrome P450 gcoa in complex with guaethol.”. X-ray diffraction, 2 ligands (HEM, 261), 4 pockets (best druggability 0.86). MolNFT v1 #129519 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5OMS
- Type
- protein
- Length
- 403 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome P450
- Ligands
- HEM, 261
- Pockets
- 4 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 57% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytochrome P450 | protein | 403 | 57% helix, 11% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 364 | 0.86 | 0.95 | 40 | HEM, 261 |
| 2 | 94 | 0.40 | 0.77 | 15 | empty |
| 3 | 59 | 0.38 | 0.80 | 17 | empty |
| 4 | 75 | 0.32 | 0.75 | 12 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5OMS · PDBe 5OMS
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