MolNFT v1 · #129006 · protein

Structural insights into the periplasmic sensor domain of the gacs histidine kinase controlling biofilm formation in pseudomonas aeruginosa

5O7J: “Structural insights into the periplasmic sensor domain of the gacs histidine kinase controlling biofilm…”. Solution nmr, 2 pockets (best druggability 0.56). MolNFT v1 #129006 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 5O7J
Type: protein
Length: 150 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Histidine kinase
EC: 2.7.13.3
UniProt: A0A0A8RMX6
Pockets: 2 · best druggability 0.56

Structure

solution nmr · 1 distinct chain · 23% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Histidine kinase (EC 2.7.13.3)	protein	150	23% helix, 11% strand	A0A0A8RMX6

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	171	0.56	0.80	31	empty
2	54	0.32	0.77	11	empty

Compared structures

5O7J · Structural insights into the periplasmic sensor domain of the GacS histidine kinase… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0A8RMX6
Elsewhere: RCSB PDB 5O7J · PDBe 5O7J · UniProt A0A0A8RMX6

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