MolNFT v1 · #128921 · protein
Structure of the inactive T.MARITIMA pde (TM1595) D80N D154N mutant with substrate 5'-papa
5O4Z · DHH/DHHA1-type phosphodiesterase TM1595: “Structure of the inactive T.MARITIMA pde (TM1595) D80N D154N mutant with substrate 5'-papa”. X-ray diffraction, 3 ligands (A, SO4, CL), 1 pocket (best druggability 0.79). MolNFT v1 #128921…
- PDB
- 5O4Z
- Type
- protein
- Length
- 323 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DHH/DHHA1-type phosphodiesterase TM1595
- UniProt
- Q9X1T1
- Ligands
- A, SO4, CL
- Pockets
- 1 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DHH/DHHA1-type phosphodiesterase TM1595 | protein | 323 | 44% helix, 19% strand | Q9X1T1 |
Ligands and binding sites
- A · Adenosine-5'-monophosphate · ligand · 2 copies · chains A
- SO4 · Sulfate ion · ion · 6 copies · chains A
- CL · Chloride ion · ion · 2 copies · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1132 | 0.79 | 0.81 | 75 | A, SO4, GOL |
Compared structures
- 5O4Z · Structure of the inactive T.maritima PDE (TM1595) D80N D154N mutant with substrate 5'-pApA · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X1T1
- Elsewhere: RCSB PDB 5O4Z · PDBe 5O4Z · UniProt Q9X1T1
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