MolNFT v1 · #128775 · protein
Crystal structure of trans-membrane domain of cylindrospermum stagnale NADPH-oxidase 5 (NOX5)
5O0T · Putative ferric reductase: “Crystal structure of trans-membrane domain of cylindrospermum stagnale NADPH-oxidase 5 (NOX5)”. X-ray diffraction, 4 ligands (D10, HEM, LFA), 3 pockets (best druggability 0.71). MolNFT v1 #128775 on…
- PDB
- 5O0T
- Type
- protein
- Length
- 206 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative ferric reductase
- UniProt
- K9WT99
- Ligands
- D10, HEM, LFA, SO4
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 84% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative ferric reductase | protein | 206 | 84% helix, 0% strand | K9WT99 |
Ligands and binding sites
- D10 · Decane · ligand · 3 copies · chains A
- HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A
- LFA · Eicosane · ligand · 2 copies · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A
- PEG · Di(hydroxyethyl)ether · additive · 4 copies · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 323 | 0.71 | 0.84 | 40 | HEM |
| 2 | 343 | 0.68 | 0.81 | 34 | HEM |
| 3 | 225 | 0.59 | 0.79 | 24 | LFA |
Compared structures
- 5O0T · CRYSTAL STRUCTURE OF TRANS-MEMBRANE DOMAIN OF Cylindrospermum stagnale NADPH-OXIDASE 5… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt K9WT99
- Elsewhere: RCSB PDB 5O0T · PDBe 5O0T · UniProt K9WT99
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