MolNFT v1 · #128769 · protein
Deglycosylated nogo receptor with native disulfide structure 4
5O0N · Reticulon-4 receptor: “Deglycosylated nogo receptor with native disulfide structure 4”. X-ray diffraction, 4 ligands (NAG, MAN, BMA), 1 pocket (best druggability 0.31). MolNFT v1 #128769 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5O0N
- Type
- protein
- Length
- 310 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Reticulon-4 receptor
- UniProt
- Q99PI8
- Ligands
- NAG, MAN, BMA, CL
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Reticulon-4 receptor | protein | 310 | 6% helix, 16% strand | Q99PI8 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 6 copies · chains A
- MAN · alpha-D-mannopyranose · sugar · 4 copies
- BMA · beta-D-mannopyranose · sugar · 2 copies
- CL · Chloride ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 70 | 0.31 | 0.74 | 16 | empty |
Modifications
Observed in the structure: 5 disulfide, 3 glycan (disulfide, N-glycosylation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99PI8
- Elsewhere: RCSB PDB 5O0N · PDBe 5O0N · UniProt Q99PI8
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