MolNFT v1 · #128723 · protein
A disulfide switch determines proteolytic resistance in the birch pollen allergen bet V 2
5NZB · Profilin-2: “A disulfide switch determines proteolytic resistance in the birch pollen allergen bet V 2”. X-ray diffraction, 1 pocket (best druggability 0.29). MolNFT v1 #128723 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5NZB
- Type
- protein
- Length
- 132 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Profilin-2
- UniProt
- A4K9Z8
- Pockets
- 1 · best druggability 0.29
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Profilin-2 | protein | 132 | 31% helix, 33% strand | A4K9Z8 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 67 | 0.29 | 0.74 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5NZB · A disulfide switch determines proteolytic resistance in the birch pollen allergen Bet v 2 · the same entry in another collection · chain A against A, TM-score 1.00
- A4K9Z8 · AlphaFold monomer V2.0 prediction for profilin-2 (A4K9Z8) · a predicted model of the same protein · chain A against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4K9Z8
- Elsewhere: RCSB PDB 5NZB · PDBe 5NZB · UniProt A4K9Z8
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