MolNFT v1 · #128718 · protein

A C145S mutant of nesterenkonia AN1 amidase from the nitrilase superfamily

5NZ5: “A C145S mutant of nesterenkonia AN1 amidase from the nitrilase superfamily”. X-ray diffraction, 2 pockets (best druggability 0.41). MolNFT v1 #128718 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5NZ5
Type: protein
Length: 259 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Amidase
EC: 3.5.1.4
UniProt: D0VWZ1
Pockets: 2 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 35% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Amidase (EC 3.5.1.4)	protein	259	35% helix, 27% strand	D0VWZ1

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.41	0.79	21	empty
2	55	0.27	0.74	11	empty

Compared structures

5NZ5 · A C145S mutant of Nesterenkonia AN1 amidase from the nitrilase superfamily · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D0VWZ1
Elsewhere: RCSB PDB 5NZ5 · PDBe 5NZ5 · UniProt D0VWZ1

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