MolNFT v1 · #128686 · protein
A C145A mutant of nesterenkonia AN1 amidase bound to nicotinamide
5NY7: “A C145A mutant of nesterenkonia AN1 amidase bound to nicotinamide”. X-ray diffraction, 2 ligands (NCA, CL), 2 pockets (best druggability 0.40). MolNFT v1 #128686 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5NY7
- Type
- protein
- Length
- 262 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Amidase
- EC
- 3.5.1.4
- UniProt
- D0VWZ1
- Ligands
- NCA, CL
- Pockets
- 2 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amidase (EC 3.5.1.4) | protein | 262 | 34% helix, 27% strand | D0VWZ1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.40 | 0.80 | 22 | NCA |
| 2 | 52 | 0.26 | 0.74 | 11 | empty |
Modifications
Observed in the structure: 1 modified (oxidation).
Compared structures
- 5NY7 · A C145A mutant of Nesterenkonia AN1 amidase bound to nicotinamide · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D0VWZ1
- Elsewhere: RCSB PDB 5NY7 · PDBe 5NY7 · UniProt D0VWZ1
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