MolNFT v1 · #128653 · protein
Crystal structure of neanderthal adenylosuccinate lyase (adsl) in complex with its products AMP and fumarate
5NX9: “Crystal structure of neanderthal adenylosuccinate lyase (adsl) in complex with its products AMP and fumarate”. X-ray diffraction, 4 ligands (AMP, FUM, 2SA). MolNFT v1 #128653 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5NX9
- Type
- protein
- Length
- 1,860 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Ligands
- AMP, FUM, 2SA, CL
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 466 | — | — |
| B | — | protein | 476 | — | — |
| C | — | protein | 441 | — | — |
| D | — | protein | 477 | — | — |
Ligands and binding sites
- AMP · Adenosine monophosphate · ligand · 2 copies · chains A, B, D, C
- FUM · Fumaric acid · ligand · 2 copies · chains A, B, D, C
- 2SA · 2-[9-(3,4-dihydroxy-5-phosphonooxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ylamino]-succinic acid · ligand · 2 copies · chains A, B, C, D
- CL · Chloride ion · ion · 6 copies · chains A, B, C, D
- PEG · Di(hydroxyethyl)ether · additive · 13 copies · chains A, C, B, D
- GOL · Glycerol · additive · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5NX9 · Crystal structure of Neanderthal Adenylosuccinate Lyase (ADSL) in complex with its… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5NX9 · PDBe 5NX9
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