MolNFT v1 · #128550 · protein

Structure of human holo plasma RBP4

5NU7 · Retinol-binding protein 4: “Structure of human holo plasma RBP4”. X-ray diffraction, 2 ligands (RTL, CL), 1 pocket (best druggability 0.80). MolNFT v1 #128550 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5NU7
Type: protein
Length: 174 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Retinol-binding protein 4
UniProt: P02753
Ligands: RTL, CL
Pockets: 1 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Retinol-binding protein 4	protein	174	11% helix, 47% strand	P02753

Ligands and binding sites

RTL · Retinol · ligand · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	207	0.80	0.94	30	RTL

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

5NU7 · Structure of human holo plasma RBP4 · the same entry in another collection · chain A against A, TM-score 1.00
P02753 · AlphaFold monomer V2.0 prediction for retinol-binding protein 4 (P02753) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02753
Elsewhere: RCSB PDB 5NU7 · PDBe 5NU7 · UniProt P02753

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