MolNFT v1 · #128541 · protein
Crystal structure of human MPS1 (ttk) C604Y mutant in complex with nms-P715
5NTT: “Crystal structure of human MPS1 (ttk) C604Y mutant in complex with nms-P715”. X-ray diffraction, 1 ligand (SVE). MolNFT v1 #128541 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5NTT
- Type
- protein
- Length
- 277 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P33981
- Ligands
- SVE
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 277 | — | P33981 |
Ligands and binding sites
- SVE · N-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy) phenyl}amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide · ligand · chains A
- EDO · 1,2-ethanediol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5NTT · Crystal structure of human Mps1 (TTK) C604Y mutant in complex with NMS-P715 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P33981
- Elsewhere: RCSB PDB 5NTT · PDBe 5NTT · UniProt P33981
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.