MolNFT v1 · #128445 · protein
Human PARP14 (ARTD8), catalytic fragment in complex with an N-aryl piperazine inhibitor
5NQE: “Human PARP14 (ARTD8), catalytic fragment in complex with an N-aryl piperazine inhibitor”. X-ray diffraction, 1 ligand (94Z). MolNFT v1 #128445 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5NQE
- Type
- protein
- Length
- 360 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q460N5
- Ligands
- 94Z
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 180 | — | Q460N5 |
Ligands and binding sites
- 94Z · 3-[[4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxidanylidene-butanoyl]amino]benzamide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5NQE · Human PARP14 (ARTD8), catalytic fragment in complex with an N-aryl piperazine inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
- Q460N5 · AlphaFold monomer V2.0 prediction for protein mono-ADP- ribosyltransferase PARP14 (Q460N5) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q460N5
- Elsewhere: RCSB PDB 5NQE · PDBe 5NQE · UniProt Q460N5
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