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MolNFT v1 · #128297 · protein

Chicken grifin (crystallisation pH: 4.6)

5NM6 · Galectin: “Chicken grifin (crystallisation pH: 4.6)”. X-ray diffraction, 1 pocket (best druggability 0.53). MolNFT v1 #128297 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5NM6
Type
protein
Length
275 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Galectin
UniProt
F1NZ18
Pockets
1 · best druggability 0.53

Structure

x-ray diffraction · 2 distinct chains · 2% helix, 58% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGalectinprotein1382% helix, 57% strandF1NZ18
BGalectinprotein1372% helix, 59% strandF1NZ18

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11440.530.8026empty

Interfaces

1 interface between chains.

  • A–B · 510 Ų buried · 10 hydrogen bonds · protein-protein

Compared structures

  • 5NM6 · Chicken GRIFIN (crystallisation pH: 4.6) · the same entry in another collection · chain A against A, TM-score 1.00

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