MolNFT v1 · #128248 · protein
Human dihydropyrimidinase-related protein 4 (DPYSL4, CRMP3, ulip-4)
5NKS: “Human dihydropyrimidinase-related protein 4 (DPYSL4, CRMP3, ulip-4)”. X-ray diffraction, 3 pockets (best druggability 0.67). MolNFT v1 #128248 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5NKS
- Type
- protein
- Length
- 490 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dihydropyrimidinase-related protein 4
- UniProt
- O14531
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dihydropyrimidinase-related protein 4 | protein | 490 | 36% helix, 22% strand | O14531 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 269 | 0.67 | 0.83 | 43 | empty |
| 2 | 168 | 0.53 | 0.80 | 21 | empty |
| 3 | 53 | 0.36 | 0.79 | 11 | empty |
Compared structures
- 5NKS · Human Dihydropyrimidinase-related Protein 4 (DPYSL4, CRMP3, ULIP-4) · the same entry in another collection · chain A against A, TM-score 1.00
- O14531 · AlphaFold monomer V2.0 prediction for dihydropyrimidinase-related protein 4 (O14531) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14531
- Elsewhere: RCSB PDB 5NKS · PDBe 5NKS · UniProt O14531
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