MolNFT v1 · #127933 · protein

Complement factor D in complex with the inhibitor (2S,4R)-4-fluoro- pyrrolidine-1,2-dicarboxylic acid 1-[(1-carbamoyl-1H-indol-3-yl)- amide] 2-[(3-trifluoromethoxy-phenyl)-amide]

5NBA: “Complement factor D in complex with the inhibitor (2S,4R)-4-fluoro- pyrrolidine-1,2-dicarboxylic acid…”. X-ray diffraction, 1 ligand (8S5). MolNFT v1 #127933 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5NBA
Type: protein
Length: 225 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P00746
Ligands: 8S5

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	225	—	P00746

Ligands and binding sites

8S5 · (2~{S},4~{R})-~{N}1-(1-aminocarbonylindol-3-yl)-4-fluoranyl-~{N}2-[3-(trifluoromethyloxy) phenyl]pyrrolidine-1,2-dicarboxamide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5NBA · Complement factor D in complex with the inhibitor… · the same entry in another collection · chain A against A, TM-score 1.00
P00746 · AlphaFold monomer V2.0 prediction for complement factor D (P00746) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00746
Elsewhere: RCSB PDB 5NBA · PDBe 5NBA · UniProt P00746

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