MolNFT v1 · #127891 · protein

Crystal structure of the full-length feline immunodeficiency virus capsid protein unveils original features

5NA2 · Capsid protein (P24): “Crystal structure of the full-length feline immunodeficiency virus capsid protein unveils original features”. X-ray diffraction, 1 pocket (best druggability 0.85). MolNFT v1 #127891 on GenesisL1: 3D structure…

PDB: 5NA2
Type: protein
Length: 422 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Capsid protein (P24)
UniProt: P16087
Pockets: 1 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 60% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Capsid protein (P24)	protein	211	60% helix, 4% strand	P16087

Ligands and binding sites

GOL · Glycerol · additive · 6 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1015	0.85	0.86	120	empty

Interfaces

1 interface between chains.

A–B · 1140 Å² buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

5NA2 · Crystal structure of the full-length Feline Immunodeficiency Virus capsid protein unveils… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P16087
Elsewhere: RCSB PDB 5NA2 · PDBe 5NA2 · UniProt P16087

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