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MolNFT v1 · #127887 · protein

The full-length structure of zntb

5N9Y · Zinc transport protein zntb: “The full-length structure of zntb”. Electron microscopy, 20 pockets (best druggability 0.89). MolNFT v1 #127887 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5N9Y
Type
protein
Length
1,635 residues
Chains
5
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Zinc transport protein zntb
UniProt
P64423
Pockets
20 · best druggability 0.89

Structure

electron microscopy · 1 distinct chain · 48% helix, 12% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, D, EZinc transport protein zntbprotein32748% helix, 12% strandP64423

Pockets

20 pockets found on a 1 Å grid, 16 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111620.890.90127empty
24460.710.8152empty
37380.710.7860empty
44110.680.8052empty
54280.680.8057empty

Interfaces

9 interfaces between chains.

  • A–E · 2386 Ų buried · 24 hydrogen bonds · protein-protein
  • D–E · 2346 Ų buried · 22 hydrogen bonds · protein-protein
  • B–C · 2337 Ų buried · 21 hydrogen bonds · protein-protein
  • C–D · 2316 Ų buried · 17 hydrogen bonds · protein-protein
  • A–B · 2314 Ų buried · 26 hydrogen bonds · protein-protein

Compared structures

  • 5N9Y · The full-length structure of ZntB · the same entry in another collection · chain A against A, TM-score 1.00
  • P64423 · AlphaFold monomer V2.0 prediction for zinc transport protein zntb (P64423) · a predicted model of the same protein · chain A against A, TM-score 0.93

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