MolNFT v1 · #127817 · protein

Glycosyltransferase in lps biosynthesis

5N7Z · Lipopolysaccharide 1,6-galactosyltransferase: “Glycosyltransferase in lps biosynthesis”. X-ray diffraction, 2 pockets (best druggability 0.62). MolNFT v1 #127817 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5N7Z
Type: protein
Length: 357 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lipopolysaccharide 1,6-galactosyltransferase
EC: 2.4.1.-
UniProt: Q06994
Pockets: 2 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lipopolysaccharide 1,6-galactosyltransferase (EC 2.4.1.-)	protein	357	42% helix, 18% strand	Q06994

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	470	0.62	0.76	60	empty
2	104	0.43	0.77	18	empty

Compared structures

5N7Z · glycosyltransferase in LPS biosynthesis · the same entry in another collection · chain A against A, TM-score 1.00
Q06994 · AlphaFold monomer V2.0 prediction for lipopolysaccharide 1,6-galactosyltransferase… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q06994
Elsewhere: RCSB PDB 5N7Z · PDBe 5N7Z · UniProt Q06994

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