MolNFT v1 · #127792 · protein
Crystal structure of the apo-form of the co dehydrogenase accessory protein coot from rhodospirillum rubrum
5N76: “Crystal structure of the apo-form of the co dehydrogenase accessory protein coot from rhodospirillum rubrum”. X-ray diffraction, 5 pockets (best druggability 0.74). MolNFT v1 #127792 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5N76
- Type
- protein
- Length
- 371 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Coot
- UniProt
- P72320
- Pockets
- 5 · best druggability 0.74
Structure
x-ray diffraction · 3 distinct chains · 0% helix, 65% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D, E | Coot | protein | 62 | 0% helix, 65% strand | P72320 |
| B, C | Coot | protein | 63 | 0% helix, 65% strand | P72320 |
| F | Coot | protein | 59 | 0% helix, 66% strand | P72320 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 416 | 0.74 | 0.84 | 54 | empty |
| 2 | 112 | 0.45 | 0.79 | 24 | empty |
| 3 | 101 | 0.41 | 0.77 | 22 | empty |
| 4 | 69 | 0.32 | 0.76 | 23 | empty |
| 5 | 66 | 0.32 | 0.76 | 23 | empty |
Interfaces
6 interfaces between chains.
- B–C · 856 Ų buried · 13 hydrogen bonds · protein-protein
- E–F · 821 Ų buried · 14 hydrogen bonds · protein-protein
- A–D · 820 Ų buried · 15 hydrogen bonds · protein-protein
- D–B · 456 Ų buried · 8 hydrogen bonds · protein-protein
- B–F · 419 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5N76 · Crystal structure of the apo-form of the CO dehydrogenase accessory protein CooT from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P72320
- Elsewhere: RCSB PDB 5N76 · PDBe 5N76 · UniProt P72320
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