MolNFT v1 · #127707 · protein

N-terminal domain of a human coronavirus NL63 nucleocapsid protein

5N4K · Nucleoprotein: “N-terminal domain of a human coronavirus NL63 nucleocapsid protein”. X-ray diffraction, 1 ligand (SO4), 3 pockets (best druggability 0.76). MolNFT v1 #127707 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 5N4K
Type: protein
Length: 259 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoprotein
UniProt: Q6Q1R8
Ligands: SO4
Pockets: 3 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoprotein	protein	130	5% helix, 27% strand	Q6Q1R8
B	Nucleoprotein	protein	129	5% helix, 27% strand	Q6Q1R8

Ligands and binding sites

SO4 · Sulfate ion · ion · 14 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	955	0.76	0.79	63	SO4
2	201	0.52	0.77	40	empty
3	171	0.49	0.77	33	SO4

Interfaces

1 interface between chains.

A–B · 1339 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

5N4K · N-terminal domain of a human Coronavirus NL63 nucleocapsid protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6Q1R8
Elsewhere: RCSB PDB 5N4K · PDBe 5N4K · UniProt Q6Q1R8

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