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MolNFT v1 · #127622 · protein

Crystal structure of the BCL6 btb domain in complex with pyrazolo- pyrimidine macrocyclic ligand

5N1Z · B-cell lymphoma 6 protein: “Crystal structure of the BCL6 btb domain in complex with pyrazolo- pyrimidine macrocyclic ligand”. X-ray diffraction, 2 ligands (8GQ, CL). MolNFT v1 #127622 on GenesisL1: 3D structure, binding sites and…

PDB
5N1Z
Type
protein
Length
123 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
B-cell lymphoma 6 protein
UniProt
P41182
Ligands
8GQ, CL

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AB-cell lymphoma 6 proteinprotein12352% helix, 11% strandP41182

Ligands and binding sites

  • 8GQ · pyrazolo-pyrimidine macrocycle · ligand · chains A
  • CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5N1Z · Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine macrocyclic… · the same entry in another collection · chain A against A, TM-score 1.00
  • P41182 · AlphaFold monomer V2.0 prediction for B-cell lymphoma 6 protein (P41182) · a predicted model of the same protein · chain A against A, TM-score 0.32

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