MolNFT v1 · #127432 · protein

Crystal structure of the BCL6 btb-domain with compound 2

5MWD · B-cell lymphoma 6 protein: “Crystal structure of the BCL6 btb-domain with compound 2”. X-ray diffraction, 1 ligand (TJ3). MolNFT v1 #127432 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5MWD
Type: protein
Length: 122 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: B-cell lymphoma 6 protein
UniProt: P41182
Ligands: TJ3

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	B-cell lymphoma 6 protein	protein	122	52% helix, 11% strand	P41182

Ligands and binding sites

TJ3 · 5-[[5-chloranyl-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]amino]-1,3-dihydroindol-2-one · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5MWD · Crystal structure of the BCL6 BTB-domain with compound 2 · the same entry in another collection · chain A against A, TM-score 1.00
P41182 · AlphaFold monomer V2.0 prediction for B-cell lymphoma 6 protein (P41182) · a predicted model of the same protein · chain A against A, TM-score 0.32

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P41182
Elsewhere: RCSB PDB 5MWD · PDBe 5MWD · UniProt P41182

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