MolNFT v1 · #127421 · protein

Crystal structure of BCL-6 btb-domain with bi-3802

5MW2 · B-cell lymphoma 6 protein: “Crystal structure of BCL-6 btb-domain with bi-3802”. X-ray diffraction, 1 ligand (U52). MolNFT v1 #127421 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5MW2
Type: protein
Length: 122 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: B-cell lymphoma 6 protein
UniProt: P41182
Ligands: U52

Structure

x-ray diffraction · 1 distinct chain · 53% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	B-cell lymphoma 6 protein	protein	122	53% helix, 11% strand	P41182

Ligands and binding sites

U52 · 2-[6-[[5-chloranyl-2-[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxidanylidene-quinolin-3-yl]oxy-~{N}-methyl-ethanamide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5MW2 · CRYSTAL STRUCTURE OF BCL-6 BTB-domain with BI-3802 · the same entry in another collection · chain A against A, TM-score 1.00
P41182 · AlphaFold monomer V2.0 prediction for B-cell lymphoma 6 protein (P41182) · a predicted model of the same protein · chain A against A, TM-score 0.32

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P41182
Elsewhere: RCSB PDB 5MW2 · PDBe 5MW2 · UniProt P41182

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