MolNFT v1 · #127395 · DNA

Solution structure of a human G-quadruplex hybrid-2 form in complex with a gold-ligand.

5MVB · DNA (26-mer): “Solution structure of a human G-quadruplex hybrid-2 form in complex with a gold-ligand.”. Solution nmr, 2 ligands (AUZ, K), 1 pocket (best druggability 0.36). MolNFT v1 #127395 on GenesisL1: 3D structure, binding…

PDB: 5MVB
Type: DNA
Length: 26 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA (26-mer)
Ligands: AUZ, K
Pockets: 1 · best druggability 0.36

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA (26-mer)	dna	26	—	—

Ligands and binding sites

AUZ · bis(m2-Oxo)-bis(2-methyl-2,2'-bipyridine)-di-gold(iii) · ligand · chains A
K · Potassium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	100	0.36	0.75	8	AUZ

Compared structures

5MVB · Solution structure of a human G-Quadruplex hybrid-2 form in complex with a Gold-ligand. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 5MVB · PDBe 5MVB

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.