MolNFT v1 · #12726 · protein

Structure and function of a virally encoded fungal toxin from ustilago maydis: a fungal and mammalian calcium channel inhibitor

1KPT · KP4 toxin: “Structure and function of a virally encoded fungal toxin from ustilago maydis: a fungal and mammalian calcium…”. X-ray diffraction, 1 pocket (best druggability 0.62). MolNFT v1 #12726 on GenesisL1: 3D structure, binding…

PDB: 1KPT
Type: protein
Length: 210 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: KP4 toxin
UniProt: Q90121
Pockets: 1 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	KP4 toxin	protein	105	31% helix, 27% strand	Q90121

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	195	0.62	0.83	34	empty

Interfaces

1 interface between chains.

A–B · 440 Å² buried · 10 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 10 disulfide (disulfide).

Compared structures

1KPT · Structure and function of a virally encoded fungal toxin from ustilago maydis: a fungal… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q90121
Elsewhere: RCSB PDB 1KPT · PDBe 1KPT · UniProt Q90121

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.