MolNFT v1 · #127258 · protein

Human scbd (sorcin calcium binding domain) in complex with doxorubicin

5MRA: “Human scbd (sorcin calcium binding domain) in complex with doxorubicin”. X-ray diffraction, 2 ligands (DM2, MG). MolNFT v1 #127258 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5MRA
Type: protein
Length: 668 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P30626
Ligands: DM2, MG

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	—	protein	167	—	P30626

Ligands and binding sites

DM2 · Doxorubicin · ligand · chains A, B
MG · Magnesium ion · metal · 10 copies · chains A, B, C, D
DMS · Dimethyl sulfoxide · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5MRA · human SCBD (sorcin calcium binding domain) in complex with doxorubicin · the same entry in another collection · chain A against A, TM-score 1.00
P30626 · AlphaFold monomer V2.0 prediction for sorcin (P30626) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P30626
Elsewhere: RCSB PDB 5MRA · PDBe 5MRA · UniProt P30626

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