MolNFT v1 · #127154 · protein
ABL1 kinase (T334I_D382N) in complex with asciminib and nilotinib
5MO4: “ABL1 kinase (T334I_D382N) in complex with asciminib and nilotinib”. X-ray diffraction, 2 ligands (NIL, AY7). MolNFT v1 #127154 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5MO4
- Type
- protein
- Length
- 429 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00519
- Ligands
- NIL, AY7
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 429 | — | P00519 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5MO4 · ABL1 kinase (T334I_D382N) in complex with asciminib and nilotinib · the same entry in another collection · chain A against A, TM-score 1.00
- P00519 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase ABL1 (P00519) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00519
- Elsewhere: RCSB PDB 5MO4 · PDBe 5MO4 · UniProt P00519
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