MolNFT v1 · #127143 · protein

Bacteriophage qbeta maturation protein

5MNT · A2 maturation protein: “Bacteriophage qbeta maturation protein”. X-ray diffraction, 15 pockets (best druggability 0.77). MolNFT v1 #127143 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5MNT
Type: protein
Length: 1,680 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: A2 maturation protein
UniProt: Q8LTE2
Pockets: 15 · best druggability 0.77

Structure

x-ray diffraction · 3 distinct chains · 35% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	A2 maturation protein	protein	420	35% helix, 32% strand	Q8LTE2
B	A2 maturation protein	protein	421	35% helix, 29% strand	Q8LTE2
D	A2 maturation protein	protein	419	36% helix, 32% strand	Q8LTE2

Pockets

15 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	460	0.77	0.85	67	empty
2	202	0.62	0.82	29	empty
3	80	0.61	0.89	14	empty
4	158	0.55	0.81	22	empty
5	124	0.54	0.82	27	empty

Interfaces

6 interfaces between chains.

A–D · 1054 Å² buried · 6 hydrogen bonds · protein-protein
B–C · 1002 Å² buried · 8 hydrogen bonds · protein-protein
A–B · 622 Å² buried · 5 hydrogen bonds · protein-protein
B–D · 84 Å² buried · 3 hydrogen bonds · protein-protein
A–C · 59 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

5MNT · Bacteriophage Qbeta maturation protein · the same entry in another collection · chain C against C, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8LTE2
Elsewhere: RCSB PDB 5MNT · PDBe 5MNT · UniProt Q8LTE2

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