MolNFT v1 · #127041 · protein
1.68A structure pcaf bromodomain with 4-chloro-2-methyl-5- (METHYLAMINO)PYRIDAZIN-3(2H)-one
5MKX: “1.68A structure pcaf bromodomain with 4-chloro-2-methyl-5- (METHYLAMINO)PYRIDAZIN-3(2H)-one”. X-ray diffraction, 2 ligands (82I, SO4). MolNFT v1 #127041 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5MKX
- Type
- protein
- Length
- 213 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q92831
- Ligands
- 82I, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 106 | — | Q92831 |
| B | — | protein | 107 | — | Q92831 |
Ligands and binding sites
- 82I · 4-chloranyl-2-methyl-5-(methylamino)pyridazin-3-one · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · chains A
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
- BU1 · 1,4-butanediol · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5MKX · 1.68A STRUCTURE PCAF BROMODOMAIN WITH 4-chloro-2-methyl-5-(methylamino)pyridazin-3(2H)-one · the same entry in another collection · chain A against A, TM-score 1.00
- Q92831 · AlphaFold monomer V2.0 prediction for histone acetyltransferase KAT2B (Q92831) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92831
- Elsewhere: RCSB PDB 5MKX · PDBe 5MKX · UniProt Q92831
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