MolNFT v1 · #127040 · protein
Crystal structure of the human ZRANB3 hnh domain
5MKW · DNA annealing helicase and endonuclease ZRANB3: “Crystal structure of the human ZRANB3 hnh domain”. X-ray diffraction, 1 ligand (ZN), 1 pocket (best druggability 0.51). MolNFT v1 #127040 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5MKW
- Type
- protein
- Length
- 236 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA annealing helicase and endonuclease ZRANB3
- EC
- 3.6.4.-, 3.1.-.-
- UniProt
- Q5FWF4
- Ligands
- ZN
- Pockets
- 1 · best druggability 0.51
Structure
x-ray diffraction · 2 distinct chains · 60% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA annealing helicase and endonuclease ZRANB3 (EC 3.6.4.-, 3.1.-.-) | protein | 119 | 61% helix, 10% strand | Q5FWF4 |
| B | DNA annealing helicase and endonuclease ZRANB3 (EC 3.6.4.-, 3.1.-.-) | protein | 117 | 60% helix, 10% strand | Q5FWF4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 311 | 0.51 | 0.73 | 29 | GOL |
Interfaces
1 interface between chains.
- A–B · 575 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5FWF4
- Elsewhere: RCSB PDB 5MKW · PDBe 5MKW · UniProt Q5FWF4
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