MolNFT v1 · #126721 · protein
Structure of a bacterial light-regulated adenylyl cylcase
5MBB · Beta subunit of photoactivated adenylyl cyclase: “Structure of a bacterial light-regulated adenylyl cylcase”. X-ray diffraction, 1 ligand (FMN), 9 pockets (best druggability 0.72). MolNFT v1 #126721 on GenesisL1: 3D structure…
- PDB
- 5MBB
- Type
- protein
- Length
- 677 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta subunit of photoactivated adenylyl cyclase
- UniProt
- A7BT71
- Ligands
- FMN
- Pockets
- 9 · best druggability 0.72
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta subunit of photoactivated adenylyl cyclase | protein | 338 | 42% helix, 30% strand | A7BT71 |
| B | Beta subunit of photoactivated adenylyl cyclase | protein | 339 | 44% helix, 32% strand | A7BT71 |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 896 | 0.72 | 0.77 | 56 | empty |
| 2 | 127 | 0.62 | 0.86 | 19 | FMN |
| 3 | 134 | 0.61 | 0.85 | 20 | FMN |
| 4 | 203 | 0.48 | 0.75 | 23 | empty |
| 5 | 189 | 0.47 | 0.75 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 3486 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 5MBB · Structure of a bacterial light-regulated adenylyl cylcase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7BT71
- Elsewhere: RCSB PDB 5MBB · PDBe 5MBB · UniProt A7BT71
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