MolNFT v1 · #126415 · protein

Crystal structure 4AC endoglucanase-like protein from acremonium chrysogenum

5M2D: “Crystal structure 4AC endoglucanase-like protein from acremonium chrysogenum”. X-ray diffraction, 4 pockets (best druggability 0.48). MolNFT v1 #126415 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5M2D
Type: protein
Length: 440 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endoglucanase-like protein
UniProt: A0A086T6R4
Pockets: 4 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 7% helix, 57% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Endoglucanase-like protein	protein	220	7% helix, 57% strand	A0A086T6R4

Ligands and binding sites

GOL · Glycerol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	136	0.48	0.79	30	GOL
2	94	0.46	0.81	25	GOL
3	168	0.44	0.74	27	empty
4	123	0.42	0.75	24	empty

Interfaces

1 interface between chains.

A–B · 335 Å² buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

5M2D · CRYSTAL STRUCTURE 4Ac Endoglucanase-like protein from Acremonium chrysogenum · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A086T6R4
Elsewhere: RCSB PDB 5M2D · PDBe 5M2D · UniProt A0A086T6R4

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