MolNFT v1 · #126318 · protein

Crystal structure of human ACBD3 gold domain in complex with 3A protein of aichivirus a

5LZ3 · Golgi resident protein GCP60: “Crystal structure of human ACBD3 gold domain in complex with 3A protein of aichivirus a”. X-ray diffraction, 1 pocket (best druggability 0.59). MolNFT v1 #126318 on GenesisL1: 3D structure, binding…

PDB: 5LZ3
Type: protein
Length: 158 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Golgi resident protein GCP60; 3A
UniProt: Q9H3P7, O91464
Pockets: 1 · best druggability 0.59

Structure

x-ray diffraction · 2 distinct chains · 11% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Golgi resident protein GCP60	protein	124	7% helix, 54% strand	Q9H3P7
B	3A	protein	34	26% helix, 12% strand	O91464

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	141	0.59	0.83	25	empty

Interfaces

1 interface between chains.

A–B · 1483 Å² buried · 25 hydrogen bonds · protein-protein

Compared structures

5LZ3 · Crystal structure of human ACBD3 GOLD domain in complex with 3A protein of Aichivirus A · the same entry in another collection · chain A against A, TM-score 1.00
Q9H3P7 · AlphaFold monomer V2.0 prediction for golgi resident protein GCP60 (Q9H3P7) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H3P7
Every structure of UniProt O91464
Elsewhere: RCSB PDB 5LZ3 · PDBe 5LZ3 · UniProt Q9H3P7 · UniProt O91464

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.