GL1X · GenesisL1 explorer

MolNFT v1 · #126315 · protein

Llama nanobody PORM_01

5LZ0 · Porm nanobody: “Llama nanobody PORM_01”. X-ray diffraction, 2 pockets (best druggability 0.52). MolNFT v1 #126315 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5LZ0
Type
protein
Length
247 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Porm nanobody
Pockets
2 · best druggability 0.52

Structure

x-ray diffraction · 2 distinct chains · 9% helix, 47% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APorm nanobodyprotein12311% helix, 46% strand—
BPorm nanobodyprotein1248% helix, 48% strand—

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1580.520.8719empty
2580.240.7216empty

Interfaces

1 interface between chains.

  • A–B · 126 Ų buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

  • 5LZ0 · Llama nanobody PorM_01 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

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