MolNFT v1 · #126184 · protein
Crystal structure of thermophilic tryptophan halogenase (th-hal) enzyme from streptomycin violaceusniger.
5LV9: “Crystal structure of thermophilic tryptophan halogenase (th-hal) enzyme from streptomycin violaceusniger.”. X-ray diffraction, 8 pockets (best druggability 0.89). MolNFT v1 #126184 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5LV9
- Type
- protein
- Length
- 1,022 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thermophilic tryptophan halogenase
- Pockets
- 8 · best druggability 0.89
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thermophilic tryptophan halogenase | protein | 509 | 38% helix, 21% strand | — |
| B | Thermophilic tryptophan halogenase | protein | 513 | 38% helix, 21% strand | — |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 962 | 0.89 | 0.91 | 142 | empty |
| 2 | 460 | 0.76 | 0.84 | 71 | empty |
| 3 | 486 | 0.74 | 0.83 | 63 | empty |
| 4 | 90 | 0.57 | 0.86 | 21 | empty |
| 5 | 87 | 0.52 | 0.84 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 2323 Ų buried · 22 hydrogen bonds · protein-protein
Compared structures
- 5LV9 · Crystal structure of thermophilic tryptophan halogenase (Th-Hal) enzyme from Streptomycin… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5LV9 · PDBe 5LV9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.