MolNFT v1 · #12617 · protein

Solution structure of the VAM7P px domain

1KMD · Vacuolar morphogenesis protein VAM7: “Solution structure of the VAM7P px domain”. Solution nmr, 3 pockets (best druggability 0.38). MolNFT v1 #12617 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1KMD
Type: protein
Length: 117 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Vacuolar morphogenesis protein VAM7
UniProt: P32912
Pockets: 3 · best druggability 0.38

Structure

solution nmr · 1 distinct chain · 36% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vacuolar morphogenesis protein VAM7	protein	117	36% helix, 14% strand	P32912

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	68	0.38	0.78	15	empty
2	66	0.36	0.78	15	empty
3	68	0.35	0.76	15	empty

Compared structures

1KMD · Solution structure of the VAM7P px domain · the same entry in another collection · chain A against A, TM-score 1.00
P32912 · AlphaFold monomer V2.0 prediction for vacuolar morphogenesis protein 7 (P32912) · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32912
Elsewhere: RCSB PDB 1KMD · PDBe 1KMD · UniProt P32912

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