MolNFT v1 · #125956 · protein

Structure of full length unliganded cody from bacillus subtilis

5LOJ · GTP-sensing transcriptional pleiotropic repressor cody: “Structure of full length unliganded cody from bacillus subtilis”. X-ray diffraction, 7 pockets (best druggability 0.73). MolNFT v1 #125956 on GenesisL1: 3D structure, binding…

PDB: 5LOJ
Type: protein
Length: 510 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: GTP-sensing transcriptional pleiotropic repressor cody
UniProt: P39779
Pockets: 7 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	GTP-sensing transcriptional pleiotropic repressor cody	protein	255	45% helix, 14% strand	P39779

Pockets

7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	159	0.73	0.90	25	empty
2	501	0.73	0.82	61	empty
3	140	0.64	0.86	25	empty
4	57	0.57	0.89	24	empty
5	63	0.57	0.88	22	empty

Interfaces

1 interface between chains.

A–B · 881 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

5LOJ · Structure of full length unliganded CodY from Bacillus subtilis · the same entry in another collection · chain A against A, TM-score 1.00
P39779 · AlphaFold monomer V2.0 prediction for GTP-sensing transcriptional pleiotropic repressor… · a predicted model of the same protein · chain B against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39779
Elsewhere: RCSB PDB 5LOJ · PDBe 5LOJ · UniProt P39779

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