MolNFT v1 · #125875 · protein
Plasmodium falciparum nicotinic acid mononucleotide adenylyltransferase complexed with apc
5LM3 · Nicotinate-nucleotide adenylyltransferase: “Plasmodium falciparum nicotinic acid mononucleotide adenylyltransferase complexed with apc”. X-ray diffraction, 1 ligand (APC), 1 pocket (best druggability 0.66). MolNFT v1 #125875 on…
- PDB
- 5LM3
- Type
- protein
- Length
- 201 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nicotinate-nucleotide adenylyltransferase
- EC
- 2.7.7.18
- UniProt
- Q8IE38
- Ligands
- APC
- Pockets
- 1 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) | protein | 201 | 39% helix, 18% strand | Q8IE38 |
Ligands and binding sites
- APC · Diphosphomethylphosphonic acid adenosyl ester · ligand · chains A
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 357 | 0.66 | 0.80 | 48 | APC, EDO |
Compared structures
- 5LM3 · Plasmodium falciparum nicotinic acid mononucleotide adenylyltransferase complexed with APC · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IE38
- Elsewhere: RCSB PDB 5LM3 · PDBe 5LM3 · UniProt Q8IE38
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