MolNFT v1 · #125804 · protein
Structure of hantavirus envelope glycoprotein gc in postfusion conformation
5LJZ · Envelopment polyprotein: “Structure of hantavirus envelope glycoprotein gc in postfusion conformation”. X-ray diffraction, 3 ligands (NAG, FUL, NA), 2 pockets (best druggability 0.63). MolNFT v1 #125804 on GenesisL1: 3D structure…
- PDB
- 5LJZ
- Type
- protein
- Length
- 410 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Envelopment polyprotein
- UniProt
- P08668
- Ligands
- NAG, FUL, NA
- Pockets
- 2 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 5% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Envelopment polyprotein | protein | 410 | 5% helix, 53% strand | P08668 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
- FUL · beta-L-fucopyranose · sugar · chains A
- NA · Sodium ion · metal · chains A
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 524 | 0.63 | 0.76 | 57 | empty |
| 2 | 184 | 0.47 | 0.75 | 38 | empty |
Modifications
Observed in the structure: 12 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 5LJZ · Structure of hantavirus envelope glycoprotein Gc in postfusion conformation · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08668
- Elsewhere: RCSB PDB 5LJZ · PDBe 5LJZ · UniProt P08668
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